What is the drug that should be chosen for syphilis treatment? Is syphilis all caused by sexual contact?
Syphilis is a chronic, systemic disease caused by Treponema pallidum. Mainly through sexual channels, clinical manifestations of primary syphilis, secondary syphilis, tertiary syphilis, latent syphilis, congenital syphilis and so on. In the Law of the people's Republic of China on the Prevention of Infectious Diseases, it is listed as a category of diseases for category B prevention and management.
What is the route of transmission of syphilis?
The infectivity of syphilis is very strong, the route of transmission can be divided into direct contact can be divided into sexual contact and non-sexual contact. Many people do not go to some informal places and feel inconceivable that they have syphilis. The main routes of transmission of syphilis are as follows.
1. Sexual contact transmission
Clinically silicone dildo , more than 90% of syphilis is transmitted through sexual contact with syphilis patients. The ways of sexual contact include sexual intercourse, hot kisses and hugs of skin contact. Because the skin and mucous membrane of the human genitals are thin, the blood vessels are rich, and they are in a state of extreme congestion during sexual intercourse, sexual friction can cause minor damage, creating conditions for the invasion of Treponema pallidum.
2. Indirect contact transmission
Contact with things used by syphilis patients, such as the patient's clothes, quilts, articles, supplies, tools, toilets, bath towels, etc., may be contaminated by the patient's secretions and infected with pallid Treponema pallidum. Healthy people who live closely with syphilis patients are prone to syphilis when they come into contact with pathogenic bacteria in a slight wound.
3. Blood-borne transmission
The course of syphilis is long, and Treponema pallidum can be latent in the patient's blood for a period of time. In particular, patients with latent syphilis are infected with pathogens, but there are no clinical manifestations. Blood and blood products provided by healthy people and patients with other diseases can infect blood patients with syphilis.
Attention should be paid to the principles of treatment of syphilis
Syphilis is a chronic, systematic sexually transmitted disease caused by Treponema pallidum. Mainly through sexual channels, clinical manifestations of primary syphilis, secondary syphilis, tertiary syphilis, latent syphilis, congenital syphilis and so on. In the Law of the people's Republic of China on the Prevention of Infectious Diseases, it is listed as a category of diseases for category B prevention and management.
Syphilis can be divided into the following treatments according to the disease.
1. Principles of treatment
It emphasizes early diagnosis, early treatment, regular course of treatment and adequate dose. Regular clinical and laboratory follow-up were carried out after treatment. Sexual partners must investigate Tongzhi together. Early syphilis can be cured clinically and eliminate infectivity after thorough treatment. The treatment of late syphilis can eliminate inflammation in the tissue, but the damaged tissue is difficult to repair.
Penicillin, such as water agent penicillin, procaine penicillin, bromoxacillin, etc., are priority drugs for staged syphilis. People who are allergic to penicillin can choose tetracycline, erythromycin and so on. Some patients may have Jihai reaction at the beginning of the treatment of penicillin, which can be prevented by starting with a small dose or by using other drugs. The serum was reexamined every 3 months in the first year after syphilis treatment, and then every 6 months for 3 years. Neurosyphilis and cardiovascular syphilis should be followed up for life.
2. Early syphilis (including primary and secondary syphilis and early latent syphilis)
(1) penicillin therapy bromoxol (long-term cicillin) is divided into bilateral gluteal intramuscular injection, once a week, a total of 2-3 times. Procaine penicillin g was injected intramuscularly for 10 to 15 days, with a total amount of 8 million u ~ 12 million u.
(2) tetracycline hydrochloride was taken orally for 15 days in patients with penicillin allergy. Doxycycline was taken continuously for 15 days.
3. Advanced syphilis (including tertiary skin, mucous membrane, bone syphilis, late latent syphilis) and secondary syphilis recurrence
(1) penicillin bromoxol, once a week, intramuscularly injected three times. Procaine penicillin g, intramuscular injection, for 20 days. The treatment can be repeated after an interval of two weeks.
(2) tetracycline hydrochloride was taken orally for 30 days in patients with penicillin allergy. Doxycycline, taken continuously for 30 days.
4. Neurosyphilis
Should be hospitalized, in order to avoid Ji Hai's reaction, oral prednisone one day before penicillin injection, once a day for 3 consecutive days.
The main results were as follows: (1) penicillin g was given intravenously for 14 days.
(2) Procaine penicillin g was injected intramuscularly and oral propanesulfonic acid was taken orally for 10 to 14 days.
After the above-mentioned treatment, they were given bromoxobenzene once a week, intramuscular injection for 3 weeks.
5. Syphilis during pregnancy
According to the treatment plan of syphilis in the corresponding period, one course of treatment was used within three months before pregnancy and one course of treatment was used in three months after pregnancy. Patients with penicillin allergy were treated with erythromycin, early syphilis for 15 days, secondary recurrence and late syphilis for 30 days. The born baby was repaired with penicillin.
6. Fetal syphilis (congenital syphilis)
Early congenital syphilis (less than 2 years old) cerebrospinal fluid abnormality: water penicillin g or procaine penicillin g treatment, the specific dose as directed by the doctor. Patients with normal cerebrospinal fluid: bromoxacillin g, injected once (divided into bilateral gluteal muscles). Those who check cerebrospinal fluid unconditionally can be treated as those with abnormal cerebrospinal fluid.
7. Treatment of syphilis in pregnant women
(1) married women with a history of syphilis must undergo a comprehensive syphilis test before becoming pregnant. Women who have had unclean sex or infected with syphilis had better go to a regular hospital for a comprehensive syphilis test before pregnancy. For those married women who have completed syphilis treatment and have no obvious symptoms of syphilis, they can not get pregnant until they are sure that syphilis is cured.
(2) examination and treatment of syphilis during pregnancy: serological examination of syphilis should be performed in the first 3 months and the end of pregnancy. If syphilis is found to be infected, it should be treated regularly to reduce the chance of fetal syphilis.
8. Jihai reaction in the treatment of syphilis
Fever, headache, joint pain, nausea, vomiting and syphilis rash may occur within a few hours after the first use of poison therapy, which is a Jihai reaction, and most of the symptoms will be relieved within 24 hours. In order to prevent the occurrence of Jihai reaction, penicillin can be gradually increased from a small dose to a normal dose. For neurosyphilis and cardiovascular syphilis, a short course of prednisone can be given before treatment, given in stages, and gradually discontinued 2-4 days after anti-syphilis treatment. Corticosteroids can reduce the fever of Jihai reaction bbw dildo , but the effect on local inflammation is uncertain.
What is the route of transmission of syphilis?
The infectivity of syphilis is very strong, the route of transmission can be divided into direct contact can be divided into sexual contact and non-sexual contact. Many people do not go to some informal places and feel inconceivable that they have syphilis. The main routes of transmission of syphilis are as follows.
1. Sexual contact transmission
Clinically silicone dildo , more than 90% of syphilis is transmitted through sexual contact with syphilis patients. The ways of sexual contact include sexual intercourse, hot kisses and hugs of skin contact. Because the skin and mucous membrane of the human genitals are thin, the blood vessels are rich, and they are in a state of extreme congestion during sexual intercourse, sexual friction can cause minor damage, creating conditions for the invasion of Treponema pallidum.
2. Indirect contact transmission
Contact with things used by syphilis patients, such as the patient's clothes, quilts, articles, supplies, tools, toilets, bath towels, etc., may be contaminated by the patient's secretions and infected with pallid Treponema pallidum. Healthy people who live closely with syphilis patients are prone to syphilis when they come into contact with pathogenic bacteria in a slight wound.
3. Blood-borne transmission
The course of syphilis is long, and Treponema pallidum can be latent in the patient's blood for a period of time. In particular, patients with latent syphilis are infected with pathogens, but there are no clinical manifestations. Blood and blood products provided by healthy people and patients with other diseases can infect blood patients with syphilis.
Attention should be paid to the principles of treatment of syphilis
Syphilis is a chronic, systematic sexually transmitted disease caused by Treponema pallidum. Mainly through sexual channels, clinical manifestations of primary syphilis, secondary syphilis, tertiary syphilis, latent syphilis, congenital syphilis and so on. In the Law of the people's Republic of China on the Prevention of Infectious Diseases, it is listed as a category of diseases for category B prevention and management.
Syphilis can be divided into the following treatments according to the disease.
1. Principles of treatment
It emphasizes early diagnosis, early treatment, regular course of treatment and adequate dose. Regular clinical and laboratory follow-up were carried out after treatment. Sexual partners must investigate Tongzhi together. Early syphilis can be cured clinically and eliminate infectivity after thorough treatment. The treatment of late syphilis can eliminate inflammation in the tissue, but the damaged tissue is difficult to repair.
Penicillin, such as water agent penicillin, procaine penicillin, bromoxacillin, etc., are priority drugs for staged syphilis. People who are allergic to penicillin can choose tetracycline, erythromycin and so on. Some patients may have Jihai reaction at the beginning of the treatment of penicillin, which can be prevented by starting with a small dose or by using other drugs. The serum was reexamined every 3 months in the first year after syphilis treatment, and then every 6 months for 3 years. Neurosyphilis and cardiovascular syphilis should be followed up for life.
2. Early syphilis (including primary and secondary syphilis and early latent syphilis)
(1) penicillin therapy bromoxol (long-term cicillin) is divided into bilateral gluteal intramuscular injection, once a week, a total of 2-3 times. Procaine penicillin g was injected intramuscularly for 10 to 15 days, with a total amount of 8 million u ~ 12 million u.
(2) tetracycline hydrochloride was taken orally for 15 days in patients with penicillin allergy. Doxycycline was taken continuously for 15 days.
3. Advanced syphilis (including tertiary skin, mucous membrane, bone syphilis, late latent syphilis) and secondary syphilis recurrence
(1) penicillin bromoxol, once a week, intramuscularly injected three times. Procaine penicillin g, intramuscular injection, for 20 days. The treatment can be repeated after an interval of two weeks.
(2) tetracycline hydrochloride was taken orally for 30 days in patients with penicillin allergy. Doxycycline, taken continuously for 30 days.
4. Neurosyphilis
Should be hospitalized, in order to avoid Ji Hai's reaction, oral prednisone one day before penicillin injection, once a day for 3 consecutive days.
The main results were as follows: (1) penicillin g was given intravenously for 14 days.
(2) Procaine penicillin g was injected intramuscularly and oral propanesulfonic acid was taken orally for 10 to 14 days.
After the above-mentioned treatment, they were given bromoxobenzene once a week, intramuscular injection for 3 weeks.
5. Syphilis during pregnancy
According to the treatment plan of syphilis in the corresponding period, one course of treatment was used within three months before pregnancy and one course of treatment was used in three months after pregnancy. Patients with penicillin allergy were treated with erythromycin, early syphilis for 15 days, secondary recurrence and late syphilis for 30 days. The born baby was repaired with penicillin.
6. Fetal syphilis (congenital syphilis)
Early congenital syphilis (less than 2 years old) cerebrospinal fluid abnormality: water penicillin g or procaine penicillin g treatment, the specific dose as directed by the doctor. Patients with normal cerebrospinal fluid: bromoxacillin g, injected once (divided into bilateral gluteal muscles). Those who check cerebrospinal fluid unconditionally can be treated as those with abnormal cerebrospinal fluid.
7. Treatment of syphilis in pregnant women
(1) married women with a history of syphilis must undergo a comprehensive syphilis test before becoming pregnant. Women who have had unclean sex or infected with syphilis had better go to a regular hospital for a comprehensive syphilis test before pregnancy. For those married women who have completed syphilis treatment and have no obvious symptoms of syphilis, they can not get pregnant until they are sure that syphilis is cured.
(2) examination and treatment of syphilis during pregnancy: serological examination of syphilis should be performed in the first 3 months and the end of pregnancy. If syphilis is found to be infected, it should be treated regularly to reduce the chance of fetal syphilis.
8. Jihai reaction in the treatment of syphilis
Fever, headache, joint pain, nausea, vomiting and syphilis rash may occur within a few hours after the first use of poison therapy, which is a Jihai reaction, and most of the symptoms will be relieved within 24 hours. In order to prevent the occurrence of Jihai reaction, penicillin can be gradually increased from a small dose to a normal dose. For neurosyphilis and cardiovascular syphilis, a short course of prednisone can be given before treatment, given in stages, and gradually discontinued 2-4 days after anti-syphilis treatment. Corticosteroids can reduce the fever of Jihai reaction bbw dildo , but the effect on local inflammation is uncertain.
CopyRight © 2024 maximarket2016.com