Comprehensive analysis of the etiology of soft chancre, diagnosis and treatment
[Clinical manifestations]
1. The initial number of 1 to 2 may be due to self-vaccination, and 2 to 5 clusters of satellite ulcers may appear around it. Men tend to develop in the coronary sulcus of the penis, foreskin, glans, and anus.
2. The incubation period is generally 2 to 3 days. A typical chancre starts with a small inflammatory papule rose toy , which quickly turns into pustules. After rupturing penispumpe , it forms a round or ovoid superficial ulcer. It is soft in nature and has obvious pain. It is about a few millimeters to 2 cm in diameter. The edges are irregular and piercing, surrounded by inflammatory redness. The bottom of the ulcer is covered with gray-yellow necrotic pus and purulent secretions, which is prone to bleeding.
3. Women tend to develop on the large and small labia, labial frenulum, clitoris and anus, and can also occur in the cervix and urethra. About half of the patients can develop inguinal lymphadenitis. It is more common in men and rarely in women. It is mostly on the left side. It is often unilateral, about the size of the fingertips. The surface is red, swollen, hot and painful, with fluctuations, and can form a single cavity abscess. It is easy to break, flow out thick pus, and leave scars after healing.
[Cause]
The pathogenic bacterium is Haemophilus dukrei, which is a gram stain negative bacterium. It has a short rod-shaped shape with blunt round ends, about 1.5 - 2um long and 0.0m wide. 2um, arranged in longitudinal rows, so it is also called Streptobacter, and can be arranged in parallel in several rows or in the shape of a fish school. Most of them are found outside the cell, and a few are found in clusters within the cell. It has poor heat tolerance and can die quickly at 65℃, but it has strong cold tolerance and can survive for a long time under low temperatures. [Diagnosis] Sulfonamide drugs are the first choice. You can take compound trimoxazole 4 tablets twice a day for at least 7 days; or erythromycin 0.5g 4 times a day for a total of 7 days; you can also take tetracycline 0.5g 4 times a day for a total of 10 to 20 days.
[Treatment]
According to a history of unclean sexual intercourse, one or more painful ulcers appear on the external genitalia, and painful transverse ulcers on one side of the groin, which form a "fish mouth" after rupture; Gram stain smear examination from ulcer secretions or inguinal lymph node extracts can detect Gram negative Streptocorynebacterium brevis. Diagnosis can be made by treponema pallidum test and syphilis serone-negative best penis pump anal vibrator , and bacterial culture can be carried out if necessary.
1. The initial number of 1 to 2 may be due to self-vaccination, and 2 to 5 clusters of satellite ulcers may appear around it. Men tend to develop in the coronary sulcus of the penis, foreskin, glans, and anus.
2. The incubation period is generally 2 to 3 days. A typical chancre starts with a small inflammatory papule rose toy , which quickly turns into pustules. After rupturing penispumpe , it forms a round or ovoid superficial ulcer. It is soft in nature and has obvious pain. It is about a few millimeters to 2 cm in diameter. The edges are irregular and piercing, surrounded by inflammatory redness. The bottom of the ulcer is covered with gray-yellow necrotic pus and purulent secretions, which is prone to bleeding.
3. Women tend to develop on the large and small labia, labial frenulum, clitoris and anus, and can also occur in the cervix and urethra. About half of the patients can develop inguinal lymphadenitis. It is more common in men and rarely in women. It is mostly on the left side. It is often unilateral, about the size of the fingertips. The surface is red, swollen, hot and painful, with fluctuations, and can form a single cavity abscess. It is easy to break, flow out thick pus, and leave scars after healing.
[Cause]
The pathogenic bacterium is Haemophilus dukrei, which is a gram stain negative bacterium. It has a short rod-shaped shape with blunt round ends, about 1.5 - 2um long and 0.0m wide. 2um, arranged in longitudinal rows, so it is also called Streptobacter, and can be arranged in parallel in several rows or in the shape of a fish school. Most of them are found outside the cell, and a few are found in clusters within the cell. It has poor heat tolerance and can die quickly at 65℃, but it has strong cold tolerance and can survive for a long time under low temperatures. [Diagnosis] Sulfonamide drugs are the first choice. You can take compound trimoxazole 4 tablets twice a day for at least 7 days; or erythromycin 0.5g 4 times a day for a total of 7 days; you can also take tetracycline 0.5g 4 times a day for a total of 10 to 20 days.
[Treatment]
According to a history of unclean sexual intercourse, one or more painful ulcers appear on the external genitalia, and painful transverse ulcers on one side of the groin, which form a "fish mouth" after rupture; Gram stain smear examination from ulcer secretions or inguinal lymph node extracts can detect Gram negative Streptocorynebacterium brevis. Diagnosis can be made by treponema pallidum test and syphilis serone-negative best penis pump anal vibrator , and bacterial culture can be carried out if necessary.
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